Selected publications

  • Yi L, Flamier A (co-first author), Bell G, Wu Y, Friesen M, Zheng MM , Mitalipova M, Liu XS, Young RA, Jaenisch R. (2024) MECP2 interacts with RNA polymerase II to modulate transcription in human neurons. Neuron.

  • Flamier A, Bisht P, Richards A, Tomasello D, Jaenisch R. Human iPS cell-derived sensory neurons can be infected by SARS-CoV-2 strain WA1/2020 as well as variants delta and omicron. iScience. 2023. doi: 10.1016/j.isci.2023.107690

  • Zhang L, Bisht P, Flamier A, Barrasa MI, Friesen M, Richards A, Hughes SH, Jaenisch R. LINE1-Mediated Reverse Transcription and Genomic Integration of SARS-CoV-2 mRNA Detected in Virus-Infected but Not in Viral mRNA-Transfected Cells. Viruses. 2023 Feb 25;15(3):629. doi: 10.3390/v15030629.

  • Hanna R, Flamier A, Barabino A, Bernier G. (2021) G-quadruplexes originating from evolutionary conserved L1 elements interfere with neuronal gene expression in Alzheimer's disease. Nat. Commun. doi: 10.1038/s41467-021-22129-9.

  • Flamier A, El Hajjar J, Adjaye J, Fernandes K, Abdouh M and Bernier G. (2018) Modeling late-onset sporadic Alzheimer's disease through BMI1 deficiency. Cell Reports. doi: 10.1016/j.celrep.2018.04.097.

  • Barabino A, Flamier A, Hanna R, Heon E, Freedman B and Bernier G. (2020) Deregulation of neuro- developmental genes and primary cilium cystoskeleton anomalies in iPSC retinal sheets from human syndromic ciliopathies. Stem Cell Reports. doi: 10.1016/j.stemcr.2020.02.005.

  • Zhou S, Flamier A (co-first author), Abdouh M, Tetreault N, Barabino A, Wadhwa S, and Bernier G (2015). Differentiation of human embryonic stem cells into cone photoreceptors through simultaneous inhibition of BMP/TGFb/WNT signalling. Development. doi: 10.1242/dev.125385.

  • Popovic N, Hooker E, Barabino A, Flamier A, Provost F, Bernier G and Larrivee B. (2021) COCO/DAND5 inhibits developmental and pathological ocular angiogenesis. EMBO. doi: 10.15252/emmm.202012005.

  • Flamier A, Abdouh M, Hamam R, Barabino A, Patel N, Gao A, Hanna R and Bernier G. (2019) Off- target effect of the BMI1 inhibitor PTC596 drives epithelial-mesenchymal transition in glioblastoma multiforme. Nature Precision Oncology. doi: 10.1038/s41698-019-0106-1.

  • Abdouh M, Hanna R, Flamier A, El Hajjar J and Bernier G. (2016) The Polycomb Repressive Complex 1 Protein BMI1 is Required for Constitutive Heterochromatin Formation and Silencing in Mammalian Somatic Cells. Journal of Biological Chemistry. doi: 10.1074/jbc.M115.662403.

  • Flamier A, Singh S and Rasmussen TP. (2017) A standardized human embryoid body platform for the detection and analysis of teratogens. PlosONE. doi: 10.1371/journal.pone.0171101.